SF absolutely nailed the 2007 draft, and they killed the top of the 2010 and 2011 drafts as well. In fact, 2010 looks to be just as great as 2007 for them even though it includes the bust 2nd rounder, Taylor Mays. Gore was 2005. Davis was 2006.
Their crappy record from 3-5 years ago plus a few trades have given them multiple 1st rounders on a few occasions. They've also moved up on Draft day a few times.

Overall, they're front 12 (13 if you count Davis) is the best in the league and it ain't even close.
They seem to miss on just as many FAs as they've hit on, but I guess they manage their cap pretty well.